Нашлось упоминание в другой статье. Там пишут про эстимированные превышения доз от нескольких вакцин (что логично), и любопытное упоминание о дозе в 15mg, которая была упомянута/зафиксирована ещё в середине 20 века:
Chapter 21 of the US Code of Federal Regulations [610.15(a)] governs the amount of aluminum permitted in the recommended single human dose of a product. The amount of aluminum is limited to no >0.85 mg/dose if the level is assayed, or 1.14 mg if determined by calculation on the basis of the amount of aluminum compound added. The regulations were amended in 1981 to increase the permissible level of aluminum to 1.25 mg in biological products to make the regulations consistent with the World Health Organization standards per single human dose of a product. If aluminum compounds other than alum are used, the total amount of alum should not be more than the equivalent permitted as potassium alum, i.e. 15 mg [4]. The amount of 15 mg of alum or 0.85 mg aluminum per dose was selected empirically from data that demonstrated that this amount of aluminum enhanced the antigenicity and effectiveness of the vaccine (Joan May, FDA/CBER, personal communication).
[4] Department of Health, Education and Welfare, Public Health Service, National Institutes of Health. Minimum requirements for the amount of aluminum adjuvants in toxoids, vaccines and multiple antigens 1953.
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Date: 2017-12-21 09:09 am (UTC)Norman W. Baylor, William Egan, Paul Richman, Aluminum salts in vaccines—US perspective, In Vaccine, Volume 20, Supplement 3, 2002, Pages S18-S23, ISSN 0264-410X, https://doi.org/10.1016/S0264-410X(02)00166-4.
(http://www.sciencedirect.com/science/article/pii/S0264410X02001664)
Keywords: Aluminum; Adjuvants; Vaccines; Clinical trials
Chapter 21 of the US Code of Federal Regulations [610.15(a)] governs the amount of aluminum permitted in
the recommended single human dose of a product. The amount of aluminum is limited to no >0.85 mg/dose if the level is assayed, or 1.14 mg if determined by calculation on the basis of the amount of aluminum compound added. The regulations were amended in 1981 to increase the permissible level of aluminum to 1.25 mg in biological products to make the regulations consistent with the World Health Organization
standards per single human dose of a product. If aluminum compounds other than alum are used, the total
amount of alum should not be more than the equivalent permitted as potassium alum, i.e. 15 mg [4]. The amount of 15 mg of alum or 0.85 mg aluminum per dose was selected empirically from data that demonstrated that this amount of aluminum enhanced the antigenicity and effectiveness of the vaccine (Joan May, FDA/CBER, personal communication).
[4] Department of Health, Education and Welfare, Public Health Service, National Institutes of Health. Minimum requirements for the amount of aluminum adjuvants in toxoids, vaccines and multiple antigens 1953.